The VRC high-density Microelectrode Array setup (Multi Channel Systems GmbH, Germany), or MEA, allows simultaneous in vitro extracellular recording from multiple locations in the sample. It is located at 124 Anatomy-Chemistry Building.

Click here to sign up for the room, via the Rig Room Booking System.

 

The MEA setup includes:

• Recording chamber with the electrode array
• Perfusion system with temperature control and oxygenation capabilities
• Recording system (low noise amplifiers and custom built data acquisition software)
• Light stimulation system

MEA Layout:

• Number of recording fields: 2
• Number of electrodes in a field: 30
• Electrode layout: rectangular grid
• Electrode diameter: 10 micrometer
• Distance between electrodes: 30 micrometer
• Internal reference electrode

Stimulation system:

• full-field flashes at user-defined intervals
• full-field flicker at a specified contrast
• white noise checkerboards.
• We also have the capability to present custom-generated monochromatic stimuli from a user-supplied MATLAB file. Stimuli that we have used in the past include full-field flicker with values drawn from naturalistic distributions, correlated noise, and drifting bars.